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The HYDRUS Microstent – Mechanisms of Action and Clinical Efficacy

By ximena.balbin
December 5, 2025
Alcon Publications
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"The HYDRUS Microstent – Mechanisms of Action and Clinical Efficacy"

KEY TAKEAWAY POINTS 

 

  • The evolution of surgical glaucoma treatment has led to the development of procedures attempting to achieve better efficacy, but having variable complication profiles
  • MIGS devices have the capacity to provide efficacy and reduce complications with rapid patient recovery
  • The HYDRUS Microstent has a Tri-Modal ® mechanism of action that bypasses the trabecular meshwork, scaffolds Schlemm’s canal, and spans approximately 90° ensuringaccess to collector channels in the nasal region
  • The pivotal clinical data demonstrate that combining the HYDRUS Microstent with cataract surgery provides a durable decrease in IOP in adults with mild to moderate primary open-angle glaucoma with a concurrent decrease in medication dependence

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